ansel 1989 pengantar bentuk sediaan farmasi. pdf

The combination of gum arabic and CMC-Na gelling agents showed an increase in spreadability of gel formulas at the same concentration of composition, of which the combinations were 1.25% gum arabic and 1.25% CMC-Na. The gel dosage forms made with CMC-Na, gum arabic, and gelatin as gelling agents resulted in having a pH of 7 whilst gels made with a combination of gelling agents resulted in having a pH of 8. The homogeneity test showed that all formulations were homogeneous and contained no agglomerated particles. Results: The tests were carried out on 15 formulations respectively (R1, R2, and R3), and resulted in the production of clear, translucent yellow gel with a distinctive citronella grass odor. The gel evaluation was conducted using an organoleptic test, homogeneity test, dispersion test, pH test, and adhesion test. Methods: The gel was made using a melting method, which mixed the base of gel with citronella ethanol extract at a temperature of 40 oC to form a homogeneous phase.

As a result, researchers developed an antiseptic gel that contains this ethanol extract.Īims: This study aims to find the optimum concentration of gelling agent required to make the gel and to use physical evaluations in order to understand whether combining gelling agents may increase the quality of the gel. Introduction: The ethanol extract from citronella grass ( Cymbopogon nardus) has been found to contain saponins, phenolics (flavonoids), and polyphenols which have antibacterial activity. Atma Jaya Catholic University of Indonesia, IndonesiaĪntiseptic, Citronella Grass, Cymbopogon nardus, Gelling agent Abstract

Ansel 1989 pengantar bentuk sediaan farmasi. pdf